1693 – A powerful earthquake destroys parts of Sicily and Malta.
1787 – William Herschel discovers Titania and Oberon, two moons of Uranus.
1879 – The Anglo-Zulu War begins. The British will suffer a major defeat at the Battle of Isandlwana on 22 January.
1922 – 14 year old Canadian Leonard Thompson becomes the first person to be injected with insulin.
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